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The Present Methods of the King Institute in the Production of Vaccine Lymph
H H King1, W J Webster2, K P Menon3
1LIEUTENANT-COLONEL, I.M.S. (From the King Institute, Guindy, Madras).
The Indian Medical Gazette
|October 11, 2017
Abstract
No abstract available in PubMed .
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Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
Vaccines
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