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Complementation Tests

Complementation Tests

A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...

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Related Experiment Video

Updated: Feb 21, 2026

Detection of Plasmodium Sporozoites in Anopheles Mosquitoes using an Enzyme-linked Immunosorbent Assay

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A Complement-Fixation Test for Kala-Azar

P C Sen Gupta¹

¹Officer-in-Charge, Kala-azar Research Department, Calcutta School of Tropical Medicine.

The Indian Medical Gazette

|October 11, 2017

Summary

No abstract available in PubMed .

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