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Analytical profile of the new diuretic beta-blocking agent tienoxolol hydrochloride
C Guechot1, A Bertrand, P Cramaille
1Analytical Development Department, Laboratoires UPSA, Rueil-Malmaison, France.
Arzneimittel-Forschung
|May 1, 1988
Abstract:
Physicochemical properties, i.e. elemental analysis, spectra (NMR, MS, IR, UV), solubilities, pKa, partition coefficient, melting point, HPLC, and data on purity and stability of ethyl 2-(3-[(1,1-dimethylethyl)amino]-2-hydroxy-propoxy)-5-[(2- thienylcarbonyl)amino]benzoate hydrochloride (tienoxolol), a new drug with antihypertensive properties are reported.