Related Experiment Videos
Treatment of anismus in intractable constipation with botulinum A toxin
R I Hallan1, N S Williams, J Melling
1Surgical Unit, London Hospital, Whitechapel.
Lancet (London, England)
|September 24, 1988
Abstract:
In seven patients with anismus the striated sphincter muscle complex was selectively weakened by local injection of Clostridium botulinum type A toxin. Symptom scores improved significantly and correlated with a significant reduction in the maximum voluntary and canal squeeze pressure and a significant increase in the anorectal angle on straining. Botulinum A toxin seems to be promising treatment for some patients with anismus.