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Updated: Feb 21, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
Clinical Decision Rule to Identify Orbital Wall Fracture Among Children: Retrospective Derivation and Validation
So Hyun Paek1, Jin Hee Jung2, Young Ho Kwak1
1From the Department of Emergency Medicines, Seoul National University Hospital, Seoul.
Insights
A new 4-variable clinical decision rule can help identify orbital wall fractures in children with periorbital trauma. This tool aids emergency departments in diagnosing these common pediatric head injuries.
Area of Science:
- Pediatric Emergency Medicine
- Ophthalmology
- Radiology
Background:
- Head and face injuries are common causes of pediatric emergency department visits.
- Currently, no established clinical decision rule exists for facial computed tomography (CT) scans in children, unlike pediatric head CT rules.
- Identifying orbital wall fractures in children with periorbital trauma requires a reliable diagnostic tool.
Purpose of the Study:
- To develop and validate a clinical decision rule (CDR) for the identification of orbital wall fractures in pediatric patients presenting with periorbital trauma.
- To establish a practical tool for emergency department use to guide the need for orbital CT scans.
Main Methods:
- A retrospective derivation and validation study was conducted involving children under 18 years old who underwent orbital CT after periorbital trauma.
- Thirteen clinical signs and symptoms were analyzed as potential predictors from 16 candidate variables.
- A 4-variable predictive model was developed and validated using 3-fold cross-validation and receiver operating characteristic (ROC) curve analysis.
Main Results:
- The optimal predictive model included four variables: orbital rim tenderness, periorbural ecchymosis, painful extraocular movement, and nausea/vomiting.
- The area under the ROC curve (AUROC) for fracture prediction was 0.793 in the derivation cohort and 0.809 in the validation cohort.
- High sensitivity (96.4%-97.8%) and negative predictive values (93.4%-98.1%) were achieved. A score of 1 or higher indicated an increased fracture risk.
Conclusions:
- A 4-variable predictive model demonstrates utility in identifying clinically significant orbital wall fractures in children.
- This clinical decision rule can aid emergency physicians in managing pediatric periorbital trauma and determining the necessity of orbital CT scans.
Objectives:
Head and face injuries are leading causes of emergency department visits in children. There is yet no clinical decision rule on face CT such as pediatric head CT rules. The goal was to develop and validate a clinical decision rule for identifying orbital wall fractures in children with periorbital trauma in the emergency department.
Methods:
This was a retrospective derivation and validation study. Children younger than 18 years who underwent orbit CT after periorbital trauma were included between January 2011 and December 2013 in 3 emergency centers. Among 16 candidate clinical variables, 13 clinical signs and symptoms were selected as clinical predictors. For the fracture model, these clinical predictors were analyzed by 3-fold cross-validation. Diagnostic performance was assessed using the area under the receiver operating characteristic (AUROC) curve in both cohorts.
Results:
Four variables (orbital rim tenderness, periorbital ecchymosis, painful extraocular movement, and nausea/vomiting) had the best predictive model with the highest AUROC value. The AUROC values for fracture prediction were 0.793 (95% confidence interval, 0.741-0.844) and 0.809 (95% confidence interval, 0.742-0.877) in the derivation cohort and validation cohort, respectively. The sensitivity and negative predictive values were 96.4% and 93.4%, respectively, in the derivation cohort, and 97.8% and 98.1%, respectively, in the validation cohort. The sum of these scores ranged from 0 to 4. Patients with a sum of scores of 1 or higher showed significantly increased risk for fracture.
Conclusions:
The 4-variable predictive model can be useful for finding clinically important orbital wall fractures in children.

