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Relationship between interpersonal sensitivity and leukocyte telomere length.

Akihito Suzuki1, Yoshihiko Matsumoto2, Masanori Enokido2

  • 1Department of Psychiatry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan. suzukiakihito@hotmail.com.

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|October 12, 2017
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Summary

Higher interpersonal sensitivity is linked to shorter telomere length in healthy adults, suggesting a connection between social sensitivity and cellular aging markers. This finding highlights potential impacts on biological aging processes.

Keywords:
IPSMInterpersonal sensitivityTelomere length

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Area of Science:

  • Psychology
  • Genetics
  • Gerontology

Background:

  • Telomeres, DNA sequences at chromosome ends, serve as biological markers for cellular aging.
  • Interpersonal sensitivity, characterized by heightened awareness of others' feelings, is a risk factor for depression.
  • This study investigates the relationship between interpersonal sensitivity and telomere length in healthy individuals.

Purpose of the Study:

  • To examine the effect of interpersonal sensitivity on telomere length.
  • To determine if heightened social sensitivity is associated with accelerated cellular aging.

Main Methods:

  • 159 healthy Japanese volunteers (mean age 42.3 years) participated.
  • Interpersonal sensitivity was measured using the Japanese version of the Interpersonal Sensitivity Measure (IPSM).
  • Leukocyte telomere length was quantified using a real-time PCR method.

Main Results:

  • A significant negative correlation was found between total IPSM scores and telomere length (β = -0.163, p = 0.038).
  • Higher scores in the 'timidity' sub-scale were significantly associated with shorter telomere length (β = -0.220, p = 0.044).

Conclusions:

  • Increased interpersonal sensitivity is associated with shorter leukocyte telomere length.
  • These findings suggest that interpersonal sensitivity may influence cellular aging processes.