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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Gallbladder01:17

Gallbladder

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The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
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Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

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This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
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Drugs for Treatment of Constipation-Predominant IBS01:21

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Related Experiment Video

Updated: Feb 21, 2026

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
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Published on: August 21, 2017

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Colonic gallstone ileus.

Lee Sigmon1, Jared Rejeski1, Brandon Marion1

  • 1Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.

BMJ Case Reports
|October 12, 2017
PubMed
Summary

Gallstone ileus, a rare cause of colon obstruction, can be treated endoscopically. This case highlights a successful endoscopic intervention for gallstone ileus secondary to a cholecystocolonic fistula in an ulcerative colitis patient.

Keywords:
endoscopygastroenterologyulcerative colitis

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Biliary Surgery

Background:

  • Gallstone ileus is an uncommon cause of bowel obstruction, rarely involving the colon.
  • Colonic gallstone ileus typically presents with high morbidity and mortality, necessitating surgical intervention.
  • Ulcerative colitis is a chronic inflammatory bowel disease with potential complications.

Observation:

  • A case of gallstone ileus in the colon was observed.
  • The gallstone ileus was secondary to a cholecystocolonic fistula.
  • The patient had a history of ulcerative colitis.

Findings:

  • A cholecystocolonic fistula led to gallstone impaction in the colon, causing obstruction.
  • The condition was successfully managed using an endoscopic approach.
  • This represents a rare instance of successful non-surgical management of colonic gallstone ileus.

Implications:

  • Endoscopic intervention may be a viable alternative to surgery for select cases of colonic gallstone ileus.
  • Understanding the interplay between inflammatory bowel disease and biliary complications is crucial.
  • This case expands the therapeutic options for rare gastrointestinal obstructions.