Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcription clusters and developmental pathways - nature, nurture, noise.

Journal of cell science·2026
Same author

On the molecular basis of enduring memory in neurons, and cell fate in fibroblasts.

Nucleic acids research·2026
Same author

Reprogrammed SimCells for antimicrobial therapy.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

A retrospectively registered pilot randomized controlled trial of postbiotic administration during antibiotic treatment increases microbiome diversity and enriches health-associated taxa.

Infection and immunity·2025
Same author

Strain displacement in microbiomes via ecological competition.

Nature microbiology·2025
Same author

Bacterial warfare is associated with virulence and antimicrobial resistance.

Nature communications·2025
Same journal

Chlorinated VSLSs Surpass HCFCs in CFC-11-Equivalent Emissions for Ozone Layer Depletion in China.

Nature communications·2026
Same journal

Author Correction: Charge transfer in triphenylamine-tetrazine covalent organic frameworks for solar-driven hydrogen peroxide production.

Nature communications·2026
Same journal

Vegetation browning patterns under compound soil and atmospheric dryness in northern permafrost ecosystems.

Nature communications·2026
Same journal

Voltage imaging of CA1 pyramidal cells and SST+ interneurons reveals stability and plasticity mechanisms of spatial firing.

Nature communications·2026
Same journal

Radical-omics reveals the hydrogen-abstraction pathway of isoprene oxidation.

Nature communications·2026
Same journal

Toughening elastomer via sequentially activated multi-pathway energy dissipation.

Nature communications·2026
See all related articles

Related Experiment Video

Updated: Feb 21, 2026

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls
10:39

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

Published on: April 12, 2018

7.8K

Microfluidics with fluid walls.

Edmond J Walsh1, Alexander Feuerborn2, James H R Wheeler3

  • 1Department of Engineering Science, Osney Thermo-Fluids Laboratory, University of Oxford, Osney Mead, Oxford, OX2 0ES, UK. edmond.walsh@eng.ox.ac.uk.

Nature Communications
|October 12, 2017
PubMed
Summary
This summary is machine-generated.

Freestyle Fluidics uses fluid walls to create microfluidic circuits in seconds. This innovative method simplifies device fabrication and operation, overcoming key limitations of traditional microfluidics.

More Related Videos

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.8K
Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

8.5K

Related Experiment Videos

Last Updated: Feb 21, 2026

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls
10:39

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

Published on: April 12, 2018

7.8K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.8K
Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

8.5K

Area of Science:

  • Biotechnology
  • Materials Science
  • Fluid Dynamics

Background:

  • Microfluidics offers significant potential but faces challenges due to complex fabrication and operation.
  • Existing microfluidic devices often require intricate solid-state components and controlled environments.

Purpose of the Study:

  • To introduce Freestyle Fluidics, a novel method that simplifies microfluidic device creation and use.
  • To demonstrate a versatile platform for various biological and chemical applications.

Main Methods:

  • Circuits are printed in 2D shapes on substrates using aqueous solutions.
  • Liquids are confined by immiscible fluid walls, preventing evaporation and enabling self-healing.
  • Flow is controlled passively via surface tension and hydrostatic pressure, or actively with pumps.

Main Results:

  • Freestyle Fluidics circuits are fabricated rapidly (seconds) and are easily reconfigurable.
  • The fluid walls demonstrate resilience and self-healing properties.
  • The technology was successfully applied to cell-based inflammatory response assays and bacterial chemotaxis studies.

Conclusions:

  • Freestyle Fluidics presents a powerful and adaptable alternative to conventional microfluidic systems.
  • This method significantly reduces the complexity and time associated with microfluidic device development.
  • The technology holds promise for broader adoption of microfluidics in research and diagnostics.