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Lymphocyte subset T4/T8 ratio in systemic lupus erythematosus: correlation with disease activity, laboratory

S Nilganuwonge1, V Harisdangkul, L Rockhold

  • 1Department of Medicine, University of Mississippi Medical Center, Jackson.

Asian Pacific Journal of Allergy and Immunology
|June 1, 1988
PubMed

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T Cell Types and Functions01:24

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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