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Pediatric Liver Transplant: Techniques and Complications
Natally Horvat1, Antonio Sergio Zafred Marcelino1, Joao Vicente Horvat1
1From the Departments of Radiology (N.H., A.S.Z.M., T.R.Y., J.d.A.B.A.F., P.P., L.M.d.O.C., G.G.C.), Surgery (J.S.N., E.A.d.F., P.C.), and Interventional Radiology (F.C.C.), Hospital Sírio-Libanês, Rua Dona Adma Jafet 91, São Paulo, SP 01308-050, Brazil; and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H., J.V.H., J.d.A.B.A.F., F.C.C., G.G.C.).
Insights
Pediatric liver transplant recipients require prompt complication diagnosis. Radiologists are crucial for pre- and postoperative imaging, guiding surgery and identifying vascular, biliary, and other issues to improve patient survival.
Area of Science:
- Radiology
- Pediatric Surgery
- Hepatology
Background:
- Liver transplantation is a critical treatment for pediatric end-stage liver disease.
- Despite advances, liver transplant surgery carries significant risks and complications.
- Early complication detection is vital but challenging due to non-specific symptoms.
Purpose of the Study:
- To review imaging techniques and radiologist roles in pediatric liver transplantation.
- To outline common post-transplant complications and their imaging features.
- To provide an imaging algorithm and reporting guidelines for pediatric liver transplant patients.
Main Methods:
- Review of surgical techniques and imaging modalities.
- Analysis of normal post-transplant imaging findings.
- Description of common vascular, biliary, parenchymal, perihepatic, and neoplastic complications.
Main Results:
- Radiologists are essential for pre-operative planning and post-operative complication diagnosis.
- Key imaging findings and potential complications are detailed.
- An imaging approach algorithm and essential radiology report elements are presented.
Conclusions:
- Effective pre- and post-operative imaging is critical for managing pediatric liver transplant patients.
- Radiology facilitates surgical guidance and early diagnosis of diverse complications.
- Standardized reporting ensures optimal patient care and outcomes.
Abstract:
Liver transplant is considered to be the last-resort treatment approach for pediatric patients with end-stage liver disease. Despite the remarkable advance in survival rates, liver transplant remains an intricate surgery with significant morbidity and mortality. Early diagnosis of complications is crucial for patient survival but is challenging given the lack of specificity in clinical presentation. Knowledge of the liver and vascular anatomy of the donor and the recipient or recipients before surgery is also important to avoid complications. In this framework, radiologists play a pivotal role on the multidisciplinary team in both pre- and postoperative scenarios by providing a road map to guide the surgery and by assisting in diagnosis of complications. The most common complications after liver transplant are (a) vascular, including the hepatic artery, portal vein, hepatic veins, and inferior vena cava; (b) biliary; (c) parenchymal; (d) perihepatic; and (e) neoplastic. The authors review surgical techniques, the role of each imaging modality, normal posttransplant imaging features, types of complications after liver transplant, and information required in the radiology report that is critical to patient care. They present an algorithm for an imaging approach for pediatric patients after liver transplant and describe key points that should be included in radiologic reports in the pre- and postoperative settings. Online supplemental material is available for this article. ©RSNA, 2017.
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