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Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Doppler US in the Evaluation of Fetal Growth and Perinatal Health
Kristen R Uquillas1, Brendan H Grubbs1, Ashley E Prosper1
1From the Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine (K.R.U., B.H.G., R.H.C.), and Department of Radiology (A.E.P., E.G.G., D.K.W.), Keck School of Medicine, University of Southern California, 2020 Zonal Ave, IRD 203, Los Angeles, CA 90033.
Insights
Fetal growth restriction, diagnosed by estimated fetal weight below the 10th percentile, requires investigation and surveillance. Umbilical artery Doppler velocimetry is recommended to identify high-risk fetuses and guide delivery timing for improved outcomes.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Radiology
Background:
- Fetal growth restriction (FGR) is defined as estimated fetal weight (EFW) below the 10th percentile for gestational age.
- FGR is linked to increased risks of intrauterine demise, neonatal morbidity, and mortality.
- Accurate antenatal detection and surveillance are crucial for optimizing pregnancy outcomes.
Purpose of the Study:
- To describe accurate ultrasound (US) detection and surveillance of FGR.
- To review the literature on Doppler velocimetry in FGR management.
- To detail techniques for umbilical artery Doppler velocimetry.
Main Methods:
- Serial ultrasonography (US) for fetal growth evaluation.
- Umbilical artery Doppler velocimetry to guide management decisions.
- Review of obstetric and radiology literature on Doppler techniques in FGR.
Main Results:
- Umbilical artery Doppler velocimetry is recommended for identifying fetuses at high risk of poor outcomes.
- This technique aids in guiding the optimal timing of delivery for FGR pregnancies.
- The use of other Doppler waveforms in FGR remains investigational.
Conclusions:
- Accurate ultrasound and umbilical artery Doppler velocimetry are essential for managing fetal growth restriction.
- Identifying high-risk fetuses and optimizing delivery timing can improve pregnancy outcomes.
- Further research is needed on the application of other Doppler techniques in FGR.
Abstract:
Fetal growth restriction is commonly defined as an estimated fetal weight (EFW) that is below the 10th percentile for gestational age. It is associated with an increased risk of intrauterine demise, neonatal morbidity, and neonatal death; therefore, antenatal detection and surveillance with the optimization of delivery timing are necessary to improve pregnancy outcomes. If the estimated due date has been verified and the EFW is below the 10th percentile for gestational age, the underlying cause should be investigated, since the clinical management, outcome, and counseling options are largely dependent on the cause of the growth restriction. Serial ultrasonography (US) for the evaluation of fetal growth and umbilical artery Doppler velocimetry are used to guide pregnancy management decisions. This article describes the accurate US detection and surveillance of fetal growth restriction, discusses the current obstetric and radiology literature regarding the use of Doppler velocimetry in the setting of fetal growth restriction, and describes the techniques for performing umbilical artery Doppler velocimetry. Although various Doppler techniques have been described in the setting of fetal growth restriction, only umbilical artery Doppler assessment is recommended to identify fetuses most at risk for poor outcome and to guide the timing of delivery. The use of other Doppler waveforms in this setting remains investigational. ©RSNA, 2017.
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