A nuclear yeast gene (GCY) encodes a polypeptide with high homology to a vertebrate eye lens protein
Related Experiment Video
Updated: Oct 9, 2026

Assessment of Zebrafish Lens Nucleus Localization and Sutural Integrity
Published on: May 6, 2019
U Oechsner1, V Magdolen, W Bandlow
1Institute for Genetics and Microbiology, Munich, FRG.
Abstract:
We describe here the nuclear gene for a yeast protein showing unexpectedly high homology with mammalian aldo/keto reductases as well as with p-crystallin, one of the prominent proteins of the frog eye lens. Although it could be proven that the gene occurs as a single copy in the haploid yeast genome, replacement of the intact by a disrupted, nonfunctional allele led to no obvious phenotype, indicating that the gene is dispensable. The gene was assigned to chromosome XV. It is transcribed in vivo into an mRNA of about 1300 bases with a coding capacity for a protein of 312 amino acids (estimated Mr 35,000).
Related Concept Videos
Yeast Signaling
Protein Complexes with Interchangeable Parts
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...
Cytoskeletal Accessory Proteins
Nuclear Protein Sorting
Proteins targeted to the nucleus carry nuclear localization signals or NLS recognized by import receptors in the cytosol. Similarly, proteins with nuclear export signals are recognized by export receptors. Import and export receptors are...
Nuclear Export
NES are of three types- the canonical 10-residue long leucine-rich signal and other...
Accessory Structures of the Eye

