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Increases in Ocular Syphilis-North Carolina, 2014-2015.
Sara E Oliver1, Anna Barry Cope1,2, Jessica L Rinsky1,2
1Centers for Disease Control and Prevention, Atlanta, Georgia.
Ocular syphilis, an eye infection from Treponema pallidum, saw a 100% increase in North Carolina from 2014 to 2015. Many patients experienced vision loss, but most improved after treatment.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Epidemiology
Background:
- Ocular syphilis is an inflammatory eye condition caused by Treponema pallidum.
- Syphilis rates have been rising in the US, with ocular syphilis clusters noted in 2015.
- This study examines the epidemiology and clinical course of ocular syphilis in North Carolina.
Purpose of the Study:
- To describe the epidemiology of ocular syphilis in North Carolina.
- To detail the clinical presentation and outcomes of ocular syphilis.
- To identify demographic and clinical factors associated with ocular syphilis.
Main Methods:
- Reviewed reported syphilis cases in North Carolina (2014-2015).
- Abstracted data from health department interviews for cases with ocular symptoms.
- Analyzed medical records and conducted interviews to assess symptom duration and severity.
Main Results:
- Ocular syphilis cases increased 100% from 2014 to 2015, outpacing overall syphilis increases.
- Ocular manifestations occurred across all syphilis stages, with 38% diagnosed in early stages.
- Reduced vision was reported by 87% of interviewed patients, with 31% experiencing residual symptoms.
Conclusions:
- Ocular syphilis incidence rose in North Carolina, possibly due to increased awareness or a true increase in cases.
- Vision loss is a common outcome, but most patients achieve visual improvement post-treatment.
- Early diagnosis and treatment are crucial for managing ocular syphilis and preventing long-term visual impairment.
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