Related Experiment Video
Updated: Feb 21, 2026

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Exploring mortality among drug treatment clients: The relationship between treatment type and mortality
Belinda Lloyd1, Renee Zahnow2, Monica J Barratt3
1Turning Point, Eastern Health, 54-62 Gertrude Street, Fitzroy 3065, Victoria, Australia; Eastern Health Clinical School, Monash University, Victoria, Australia.
Aims:
Studies consistently identify substance treatment populations as more likely to die prematurely compared with age-matched general population, with mortality risk higher out-of-treatment than in-treatment. While opioid-using pharmacotherapy cohorts have been studied extensively, less evidence exists regarding effects of other treatment types, and clients in treatment for other drugs. This paper examines mortality during and following treatment across treatment modalities.
Methods:
A retrospective seven-year cohort was utilised to examine mortality during and in the two years following treatment among clients from Victoria, Australia, recorded on the Alcohol and Drug Information Service database by linking with National Death Index. 18,686 clients over a 12-month period were included. Crude (CMRs) and standardised mortality rates (SMRs) were analysed in terms of treatment modality, and time in or out of treatment.
Results:
Higher risk of premature death was associated with residential withdrawal as the last type of treatment engagement, while mortality following counselling was significantly lower than all other treatment types in the year post-treatment. Both CMRs and SMRs were significantly higher in-treatment than post-treatment.
Conclusion:
Better understanding of factors contributing to elevated mortality risk for clients engaged in, and following treatment, is needed to ensure that treatment systems provide optimal outcomes during and after treatment.
Related Concept Videos
Comparing the Survival Analysis of Two or More Groups
Drug Therapy
Antianxiety Medications
Therapeutic Drug Monitoring: Affecting Factors
Drug Dosing: Obese Patients
Drug Toxicity: Risk factors
Cancer Survival Analysis