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Treatment of rheumatoid arthritis with biological agents - as a typical and common immune-mediated inflammatory
1Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine.
Abstract:
Molecules involved in the disease process facilitated our understanding of pathogenesis of the disease with unknown etiology such as immune-mediated and inflammatory diseases. Moreover, the targeted therapies against the proposed molecular targets by biological agents provide enormous benefits to the patients and societies. Here, I will review recent progress of the biological treatment in the immune-inflammatory diseases by focusing on the rheumatoid arthritis, the disease characterized by persistent polyarthritis leading to joint destruction and disability with autoimmune features, as a role model.
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