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Cryptococcal cerebellitis in no-VIH patient.

Fabricio Andres Lasso¹, Tomas Omar Zamora Bastidas², Jorge Andrés Potosí García¹

¹Facultad de Medicina, Universidad del Cauca. Cauca, Colombia.

Colombia Medica (Cali, Colombia)

|October 13, 2017

Summary

This summary is machine-generated.

Cryptococcal cerebellitis is a rare opportunistic infection. This case highlights a fatal instance in a 65-year-old male, emphasizing the need for awareness of unusual presentations of cryptococcosis.

Keywords:

Cerebellar diseases Cryptococcosis Cryptococcus Cryptococcus neofromans Immunocompetence adult age cryptococcal meningitis

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Area of Science:

Mycology
Infectious Diseases
Neurology

Background:

Cryptococcosis, caused by Cryptococcus neoformans / C. gattii, is an opportunistic fungal infection primarily affecting immunocompromised individuals.
While meningeal involvement is common, cerebellar cryptococcosis is exceptionally rare.

Observation:

A 65-year-old male with chronic poultry exposure presented with headache, fever, seizures, and altered mental status.
Initial examination showed no meningeal signs or intracranial hypertension, but the patient later developed ataxia and dysdiadochokinesia.
Diagnosis of cryptococcal cerebellitis was confirmed via lumbar puncture and Magnetic Resonance Imaging (MRI).

Findings:

The case describes a rare instance of cryptococcal cerebellitis.
Despite antifungal therapy with amphotericin B and fluconazole, the patient succumbed to the infection.
This represents the first reported case of cryptococcal cerebellitis in the region.

Implications:

Cryptococcosis incidence is rising, particularly with the HIV/AIDS pandemic.
Cerebral parenchymal and cerebellar involvement in cryptococcosis are uncommon but serious presentations.
Increased recognition of atypical cryptococcal infections is crucial for timely diagnosis and management.