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Interval exercise increases angiogenic cell function in postmenopausal women.

Emma Harris1, Mark Rakobowchuk2, Karen M Birch3

  • 1School of Human and Health Sciences, University of Huddersfield, Huddersfield, UK.

BMJ Open Sport & Exercise Medicine
|October 13, 2017
PubMed
Summary
This summary is machine-generated.

Interval exercise, not continuous, enhances circulating angiogenic cell (CAC) communication in postmenopausal women. This suggests interval training may improve cardiovascular health by boosting angiogenic T-cells, though repeated sessions might be needed for endothelial function improvements.

Keywords:
circulating angiogenic cellsendothelial functioninterval and continuous exercisemenopause

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Area of Science:

  • Exercise physiology
  • Cardiovascular health
  • Cellular biology

Background:

  • Postmenopausal women face increased cardiovascular disease risk.
  • Exercise can mitigate this risk.
  • Differential effects of exercise types on endothelial function and angiogenic cells are not well understood.

Purpose of the Study:

  • To compare the effects of interval versus continuous exercise on endothelial function and circulating angiogenic cell (CAC) number and function in postmenopausal women.
  • To investigate if exercise intensity influences these outcomes.

Main Methods:

  • Fifteen postmenopausal women performed acute moderate-intensity continuous (CON) and interval (MOD-INT) exercise.
  • Nine participants also completed heavy-intensity interval (HEAVY-INT) exercise.
  • Brachial artery flow-mediated dilation (FMD) and CAC colony-forming capacity were measured.

Main Results:

  • No significant changes in FMD or CAC number were observed across exercise types.
  • CAC colony-forming capacity increased significantly after MOD-INT and HEAVY-INT exercise compared to baseline.
  • Continuous exercise (CON) did not significantly alter CAC colony-forming capacity.

Conclusions:

  • A single session of interval exercise enhances CAC intercellular communication more than continuous exercise.
  • This improvement may be linked to increased angiogenic T-cell function, potentially due to higher work rates in interval training.
  • Further research with repeated exercise sessions is warranted to improve FMD in this population.