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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Triaryl-Boron Functionalized Dinuclear Platinum Complexes Linked by Photoisomerizable Bpe Ligand: Luminescence and
Nan Wang1, Mingfeng Hu1, Soren K Mellerup2
1Key Laboratory of Cluster Science, Ministry of Education of China, Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, School of Chemistry, Beijing Institute of Technology , Beijing 100081, People's Republic of China.
Abstract:
We report herein a series of triarylboron-functionalized Pt(II) dinuclear complexes using a photoactive bis(4-pyridyl)ethylene (bpe) bridging unit. The new Pt(II) complexes display phosphorescence at both room temperature and 77 K. Depending on the conditions under which crystals of the complexes were grown, either the cis- or trans-isomers could be obtained. The trans and cis isomers were found to undergo light-induced isomerization in solution with the trans isomer being the dominant species.
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