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Related Experiment Videos

Isolated sphenoid sinus opacifications: a systematic review and meta-analysis.

William J Moss1, Andrey Finegersh1, Aria Jafari1

  • 1Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of California, San Diego, San Diego, CA.

International Forum of Allergy & Rhinology
|October 13, 2017
PubMed
Summary

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Isolated sphenoid sinus opacifications (ISSOs) stem from various causes, including sinusitis and neoplasms. Aggressive treatment and close monitoring are vital due to potential complications like cranial neuropathies.

Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Radiology

Background:

  • Isolated sphenoid sinus opacifications (ISSOs) are uncommon but can lead to severe complications.
  • Understanding the diverse pathologies behind ISSOs is crucial for effective management.

Purpose of the Study:

  • To systematically review and characterize the pathologies, symptoms, and treatment outcomes of patients with ISSOs.
  • To inform clinical practice regarding the diagnosis and management of ISSOs.

Main Methods:

  • A systematic review of case series was conducted using Medline, Embase, Web of Science, and Cochrane databases.
  • Data extraction followed PRISMA guidelines, focusing on pathology, symptoms, and treatment outcomes.

Main Results:

Keywords:
diseaselesionopacificationsinusitissphenoid sinussystematic review

Related Experiment Videos

  • Seventeen articles comprising 1133 ISSO patients were included.
  • Common pathologies included chronic rhinosinusitis (CRSsNP and CRSwNP), mucoceles, fungal sinusitis, and neoplasms (malignant and benign).
  • Cranial neuropathies affected 16.3% of patients, with a 1.5% surgical complication rate.

Conclusions:

  • ISSOs present with a wide range of underlying pathologies, including significant rates of neoplastic disease.
  • Patients with ISSOs require vigilant monitoring and aggressive treatment, often necessitating prompt surgical intervention.
  • Early surgical intervention, for diagnostic or therapeutic purposes, is frequently indicated for ISSOs.