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Isolated sphenoid sinus opacifications: a systematic review and meta-analysis
William J Moss1, Andrey Finegersh1, Aria Jafari1
1Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of California, San Diego, San Diego, CA.
International Forum of Allergy & Rhinology
|October 13, 2017
Summary
Isolated sphenoid sinus opacifications (ISSOs) stem from various causes, including sinusitis and neoplasms. Aggressive treatment and close monitoring are vital due to potential complications like cranial neuropathies.
Area of Science:
- Otolaryngology
- Neurosurgery
- Radiology
Background:
- Isolated sphenoid sinus opacifications (ISSOs) are uncommon but can lead to severe complications.
- Understanding the diverse pathologies behind ISSOs is crucial for effective management.
Purpose of the Study:
- To systematically review and characterize the pathologies, symptoms, and treatment outcomes of patients with ISSOs.
- To inform clinical practice regarding the diagnosis and management of ISSOs.
Main Methods:
- A systematic review of case series was conducted using Medline, Embase, Web of Science, and Cochrane databases.
- Data extraction followed PRISMA guidelines, focusing on pathology, symptoms, and treatment outcomes.
Main Results:
- Seventeen articles comprising 1133 ISSO patients were included.
- Common pathologies included chronic rhinosinusitis (CRSsNP and CRSwNP), mucoceles, fungal sinusitis, and neoplasms (malignant and benign).
- Cranial neuropathies affected 16.3% of patients, with a 1.5% surgical complication rate.
Conclusions:
- ISSOs present with a wide range of underlying pathologies, including significant rates of neoplastic disease.
- Patients with ISSOs require vigilant monitoring and aggressive treatment, often necessitating prompt surgical intervention.
- Early surgical intervention, for diagnostic or therapeutic purposes, is frequently indicated for ISSOs.