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Mandibular lymphoma.

S Vo Quang1, L Sicard1, M Samama1

  • 1Service de stomatologie et chirurgie maxillo-faciale, AP-HP, DHU FAST, GH Pitié-Salpêtrière-Charles Foix, 47-83, boulevard de l'Hôpital, 75013 Paris, France.

Journal of Stomatology, Oral and Maxillofacial Surgery
|October 13, 2017
PubMed
Summary
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B-cell lymphoblastic lymphoma (B-LBL) rarely affects the jawbone. Diagnosis of this rare oral cancer requires histopathological analysis, as imaging is often inconclusive.

Area of Science:

  • Oncology
  • Hematology
  • Oral Pathology

Background:

  • B-cell lymphoblastic lymphoma (B-LBL) is an uncommon malignancy, with oral cavity involvement representing only 3.5% of intra-oral malignant tumors.
  • Mandibular bone involvement by B-LBL is exceptionally rare, with limited documented cases.

Observation:

  • A case study of a 30-year-old female presenting with a progressive left mandibular swelling.
  • Maxillofacial CT and MRI revealed soft tissue and muscle inflammation but lacked definitive signs of osteitis.
  • A biopsy confirmed the diagnosis of intra-oral bone lymphoblastic lymphoma.

Findings:

  • Clinical presentation and radiological imaging (CT, MRI) showed non-specific inflammatory changes, hindering early diagnosis.
  • Histopathological analysis was crucial for identifying the lymphoblastic lymphoma in the mandibular bone.
Keywords:
LymphomaMandibular

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Implications:

  • This case highlights the diagnostic challenges associated with rare intra-osseous B-LBL of the mandible.
  • Emphasizes the critical role of biopsy and histopathological examination for accurate diagnosis of jaw lymphomas.
  • Underscores the need for increased awareness among clinicians regarding rare oral malignancies.