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Updated: Jul 26, 2026
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Mandibular lymphoma
S Vo Quang1, L Sicard1, M Samama1
1Service de stomatologie et chirurgie maxillo-faciale, AP-HP, DHU FAST, GH Pitié-Salpêtrière-Charles Foix, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
Introduction:
B-cell lymphoblastic lymphoma (B-LBL) rarely occurs in the oral cavity (3.5% of all intra-oral malignant tumors). Few cases of B-LBL mandibular bone involvement have been reported.
Observation:
We report the case of a 30-year-old female patient presenting with a single swelling of the left mandibular region, having grown for several weeks. Maxillo-facial CT and MRI showed inflammation of soft tissues and muscles without initial signs of osteitis, thus noncontributive to the diagnosis. A biopsy allowed diagnosing an intra-oral bone lymphoblastic lymphoma. The patient was referred to the hematooncology unit for treatment.
Discussion:
Jaw localization of non Hodgkin's lymphoma is rare. Clinical symptomatology and radiological signs are poorly contributive. The diagnosis relies on a histopathological analysis.
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