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Related Concept Videos

Patterns of Fever01:26

Patterns of Fever

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Before understanding the types and patterns of fever, it is essential to know its phases.
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Methods of reducing fever01:22

Methods of reducing fever

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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Increased Body Temperature01:25

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
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Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Tonsillitis II: Management01:26

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Related Experiment Video

Updated: Feb 21, 2026

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Approach to recurrent fever in childhood.

Gordon S Soon1, Ronald M Laxer2

  • 1Rheumatologist in the Division of Rheumatology at The Hospital for Sick Children in Toronto, Ont, and a general pediatrician in the Department of Paediatrics at North York General Hospital and St Joseph's Health Centrein Toronto. gordon.soon@sickkids.ca.

Canadian Family Physician Medecin De Famille Canadien
|October 14, 2017
PubMed
Summary

Recurrent fevers in children may indicate rare autoinflammatory diseases after infections are excluded. Early diagnosis of conditions like Familial Mediterranean fever is crucial to prevent complications.

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Area of Science:

  • Pediatrics
  • Immunology
  • Genetics

Background:

  • Fever is a common childhood illness symptom, frequently caused by infections.
  • Recurrent or periodic fever patterns warrant consideration beyond common infections.

Observation:

  • Autoinflammatory diseases, including periodic fever syndromes, are an expanding spectrum of conditions.
  • Familial Mediterranean fever is the most common inherited autoinflammatory syndrome.
  • Periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome is a common childhood periodic fever syndrome with an unknown genetic basis.

Findings:

  • When infections are excluded, autoinflammatory diseases should be considered for recurrent fevers.
  • Early recognition and treatment of Familial Mediterranean fever can prevent systemic amyloidosis.
  • Periodic fever syndromes are increasingly recognized as causes of recurrent fevers in children and adults.

Implications:

  • Thorough history and physical examination are key for early recognition and diagnosis.
  • Prompt diagnosis and treatment of autoinflammatory diseases improve patient outcomes.
  • Understanding these rare conditions is vital for effective pediatric care.