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Updated: Feb 21, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
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All-optical photoacoustic projection imaging.

Johannes Bauer-Marschallinger1, Karoline Felbermayer1, Thomas Berer1

  • 1Research Center for Non-Destructive Testing GmbH (RECENDT), Altenberger Straße 69, 4040 Linz, Austria.

Biomedical Optics Express
|October 14, 2017
PubMed
Summary

We developed all-optical photoacoustic projection imaging using fiber-optic interferometers. This technique creates 2D projection images of 3D light absorbance in samples, offering high resolution for large volumes quickly.

Keywords:
(110.2350) Fiber optics imaging(110.7170) Ultrasound(120.3180) Interferometry(170.5120) Photoacoustic imaging

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Area of Science:

  • Biomedical Optics
  • Photoacoustic Imaging
  • Optical Sensing

Background:

  • Photoacoustic imaging combines optical absorption and ultrasound detection.
  • Traditional methods face limitations in speed and resolution for large volumes.
  • All-optical detection offers potential for enhanced sensitivity and bandwidth.

Purpose of the Study:

  • To introduce and validate an all-optical photoacoustic projection imaging system.
  • To assess the performance of fiber-optic interferometers for photoacoustic signal detection.
  • To demonstrate the system's capability for high-resolution, large-volume imaging.

Main Methods:

  • Utilized an array of fiber-optic interferometers for all-optical photoacoustic signal acquisition.
  • Developed a system for generating 2D projection images from 3D light absorbance data.
  • Performed phantom measurements to evaluate system performance.

Main Results:

  • Fiber-optic detectors achieved a noise-equivalent pressure of 24 Pascal at a 10 MHz bandwidth.
  • Demonstrated the ability to acquire high-resolution projection images.
  • Successfully imaged large sample volumes within a short acquisition time.

Conclusions:

  • All-optical photoacoustic projection imaging is a viable technique for rapid, high-resolution imaging.
  • Fiber-optic interferometers provide sensitive and broadband detection for photoacoustic signals.
  • This technology holds promise for various biomedical and materials science applications.