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Updated: Feb 21, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Accurate diagnosis of prenatal cleft lip/palate by understanding the embryology
Bram Smarius1, Charlotte Loozen2, Wendy Manten3
1Division of Pediatric Plastic Surgery, Cleft Palate Team, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands. b.j.a.smarius@umcutrecht.nl.
Abstract:
Cleft lip with or without cleft palate (CP) is one of the most common congenital malformations. Ultrasonographers involved in the routine 20-wk ultrasound screening could encounter these malformations. The face and palate develop in a very characteristic way. For ultrasonographers involved in screening these patients it is crucial to have a thorough understanding of the embryology of the face. This could help them to make a more accurate diagnosis and save time during the ultrasound. Subsequently, the current postnatal classification will be discussed to facilitate the communication with the CP teams.

