Macroglossia as a presenting feature of multiple myeloma
Serkan Demirkan1, Ekin Şavk2, Alper Alp3
1Department of Dermatology and Venereology, Faculty of Medicine, Kirikkale University, Yahsihan, Kirikkale, Turkey.
Journal of Family Medicine and Primary Care
|October 14, 2017
Summary
Macroglossia, an enlarged tongue, is rarely the initial symptom of multiple myeloma. This rare presentation highlights the importance of considering uncommon signs in diagnosing this blood cancer.
Area of Science:
- Hematology
- Oncology
- Clinical Medicine
Background:
- Multiple myeloma is a malignant proliferation of plasma cells.
- Clinical manifestations of multiple myeloma are diverse.
- Macroglossia is an uncommon finding in hematologic malignancies.
Observation:
- A rare case of multiple myeloma presenting initially with macroglossia is reported.
- The enlarged tongue was the first noticeable clinical sign in this patient.
Findings:
- This case underscores that macroglossia can be an exceedingly rare presenting symptom of multiple myeloma.
- Diagnostic workup for unexplained macroglossia should include consideration of plasma cell disorders.
Implications:
- Early recognition of rare signs like macroglossia can aid in prompt multiple myeloma diagnosis.
- Broadening the differential diagnosis for macroglossia may improve patient outcomes.
- Further investigation into the pathogenesis of macroglossia in myeloma is warranted.
