Polychlorinated dibenzo-p-dioxins and dibenzofurans levels in piglet liver with various diseases

This study deals with the levels of toxic polychlorinated dibenzo-p-dioxin and furan congeners (PCDD/Fs) in the livers of piglets affected by infectious diseases using isotope dilution high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS). Seventeen toxic congeners in the liver samples infected with bacterial and viral diseases were compared. For porcine reproductive and respiratory syndrome virus (PRRSV) samples, the North American- and European-type PRRS diseases were observed. This study shows that there are significantly different levels of PCDD/Fs, present, which vary according to the types of diseases as evidenced by our analysis of the piglet liver samples.