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Related Experiment Video

Updated: Feb 20, 2026

Optical Trapping of Nanoparticles
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Optical Trapping of Nanoparticles

Published on: January 15, 2013

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Plasmonic Nanomaterial-Based Optical Biosensing Platforms for Virus Detection.

Jaewook Lee1, Kenshin Takemura2, Enoch Y Park3,4

  • 1Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya Suruga-ku, Shizuoka 422-8529, Japan. lee.jaewook@shizuoka.ac.jp.

Sensors (Basel, Switzerland)
|October 14, 2017
PubMed
Summary

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Plasmonic nanomaterials (P-NMs) offer unique optical properties for biosensing. This review highlights their application in detecting viruses and other biomolecules via optical changes after bioconjugation.

Area of Science:

  • Nanomaterials Science
  • Biotechnology
  • Optical Engineering

Background:

  • Plasmonic nanomaterials (P-NMs) exhibit valuable optical properties like SERS, LSPR, PRET, and MO effects.
  • Diverse P-NM structures, including metal nanoparticles (MNPs) and modified graphene, are synthesized for specific applications.
  • These materials show promise for advanced optical biosensing systems.

Purpose of the Study:

  • To review plasmonic nanomaterials as optical sensing platforms.
  • To explore the modification of P-NMs with biomolecules for biosensing.
  • To discuss the application of P-NMs in detecting target viruses and biomolecules.

Main Methods:

  • Chemical conjugation and thiol chemistry were used to immobilize probe biomolecules (antibodies, DNA, aptamers) onto P-NM surfaces.
Keywords:
decorated carbon nanomaterialmetal nanoparticlenanoparticlesoptical biosensing systemplasmonic nanomaterialvirus detection

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  • Optical properties of P-NMs, such as plasmonic absorbance and fluorescence, were monitored.
  • Changes in optical properties were correlated with the binding of target analytes to the immobilized probes.

    • Main Results:

    • Bioconjugation of probe molecules onto P-NMs enables specific biomolecule detection.
    • Interactions between probe biomolecules and target viruses induce measurable changes in P-NM optical properties.
    • Detected optical property changes include alterations in fluorescence, plasmonic absorbance, and diffraction angle.

    Conclusions:

    • Plasmonic nanomaterials are versatile platforms for optical biosensing.
    • The modification of P-NMs with biomolecules allows for sensitive detection of target analytes.
    • P-NMs offer significant potential for various applications in the optical biosensing field.