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Can Economic Model Transparency Improve Provider Interpretation of Cost-Effectiveness Analysis? A Response
1*Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center †Department of Medicine, Division of Clinical Decision Making, Tufts Medical Center, Boston, MA.
Making health economic analysis source code publicly available enhances credibility and value. Open publication ensures transparency, reproducibility, and innovation, outweighing concerns about intellectual property and misuse.
Area of Science:
- Health Economics
- Computational Science
- Scientific Publishing
Background:
- Health economic analyses increasingly rely on complex computer models.
- Lack of source code transparency hinders independent verification and reproducibility.
- Existing practices in other scientific fields advocate for open computational models.
Purpose of the Study:
- To advocate for the open publication of computer model source code in health economic analyses.
- To address and refute common arguments against source code transparency.
- To highlight the benefits of open publication for scientific credibility and utility.
Main Methods:
- Argumentative and critical review of current practices in health economics.
- Analysis of intellectual property and model misuse concerns related to open source code.
- Discussion of ancillary benefits of open publication, including adaptation and innovation.
Main Results:
- Open publication of source code is essential for assessing alternative assumptions and ensuring reproducibility.
- Concerns regarding intellectual property rights are minimal, and open publication can increase model value.
- Transparency through open source code reduces the risk of model misuse and facilitates evaluation.
Conclusions:
- Open publication of health economic model source code is crucial for scientific integrity and enhancing model utility.
- The benefits of increased credibility, transparency, and innovation outweigh potential challenges and harms.
- Adoption of open publication practices will advance health economics, supporting better health policy and clinical decisions.
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