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Related Experiment Videos

Web-based drug repurposing tools: a survey.

Elizabeth Sam1, Prashanth Athri1

  • 1Department of Computer Science & Engineering Amrita, University Bengaluru, India.

Briefings in Bioinformatics
|October 14, 2017
PubMed
Summary

Drug repurposing identifies new uses for existing drugs, combating high failure rates in drug discovery. This survey highlights user-friendly web tools to make computational drug repositioning accessible to more scientists.

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Area of Science:

  • Pharmacology
  • Biotechnology
  • Computational Biology

Background:

  • Drug repurposing offers a strategy to mitigate drug development failures.
  • Eroom's law highlights declining R&D efficiency in the pharmaceutical industry.
  • High-throughput technologies generate vast biological data, necessitating advanced analytics.

Purpose of the Study:

  • To survey and present available web-based tools for drug repurposing.
  • To improve accessibility of computational drug repositioning for life scientists.
  • To bridge the gap between computational and life science researchers.

Main Methods:

  • Systematic review of web-based drug repurposing tools.
  • Analysis of tool features and user-friendliness.
  • Focus on tools aiding computational analytics in drug discovery.

Main Results:

  • Identification of various web-based computational tools for drug repositioning.
  • Assessment of tool accessibility for non-computational scientists.
  • Categorization of tools based on their functionalities.

Conclusions:

  • User-friendly web tools are crucial for democratizing drug repurposing.
  • Enhanced accessibility can accelerate drug discovery and development.
  • This survey provides a valuable resource for scientists seeking drug repositioning tools.

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