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In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
Published on: August 12, 2017
Molecular Diagnostic Testing in Cardiac Transplantation
Kiran Khush1, Shirin Zarafshar2
1Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRC, Stanford, CA, 94305, USA. kiran@stanford.edu.
Purpose Of Review:
Acute rejection is one of the most feared complications of cardiac transplantation. Developing non-invasive methods for detection and surveillance of acute rejection have long been a goal for post-transplant care.
Recent Findings:
Here, we will review molecular diagnostic tests that are currently in use or under development to diagnose acute cellular rejection after cardiac transplantation. Gene expression, microRNA, molecular microscope, and cell-free DNA assays offer non-invasive alternatives to the endomyocardial biopsy for acute rejection surveillance.
