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Relationship between Sigma-1 receptor and BDNF in the visual system.

Barbara A Mysona1, Jing Zhao1, Sylvia Smith1

  • 1James and Jean Culver Vision Discovery Institute, Augusta, GA, 30912, United States; Department of Ophthalmology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, United States; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA, 30912, United States.

Experimental Eye Research
|October 17, 2017
PubMed
Summary

Activating the sigma-1 receptor (S1R) boosts brain-derived neurotrophic factor (BDNF) in the retina and optic nerve head, potentially aiding glaucoma treatment.

Keywords:
BDNFGlaucomaOptic nerve head astrocytesRetina

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