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Single-Incision Laparoscopic Surgery for Ovarian Tissue Cryopreservation
Gilad Karavani1, Natali Schachter-Safrai1, Henry H Chill1
1Department of Obstetrics and Gynecology, Hadassah Hebrew University Hospital, Jerusalem, Israel.
Journal of Minimally Invasive Gynecology
|October 17, 2017
Summary
Single-incision laparoscopic surgery (SILS) is a viable alternative to multiport laparoscopic surgery (MPLS) for ovarian tissue cryopreservation in fertility preservation patients. SILS demonstrated comparable safety and efficacy, with a trend towards preserving more ovarian tissue.
Area of Science:
- Reproductive Medicine
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Oncologic fertility preservation is crucial for patients undergoing cancer treatment.
- Ovarian tissue cryopreservation is a key strategy for preserving fertility.
- Standard multiport laparoscopic surgery (MPLS) is the established method for this procedure.
Purpose of the Study:
- To evaluate single-incision laparoscopic surgery (SILS) as an alternative to MPLS for ovarian tissue cryopreservation.
- To compare the safety and efficacy of SILS versus MPLS in oncologic fertility preservation.
Main Methods:
- Retrospective cohort study comparing SILS and MPLS in 231 patients.
- Analysis included procedure duration, complications, hospital stay, and time to chemotherapy.
- Key outcome measures were the number of cryopreserved ovarian tissue ampules and retrieved oocytes.
Main Results:
- SILS and MPLS showed similar procedure durations and overall complication rates.
- The SILS group preserved a significantly higher number of ovarian tissue ampules compared to the MPLS group (14.7 vs 10.6, p < .01).
- Patient demographics and distribution of malignant conditions were comparable between groups.
Conclusions:
- Single-incision laparoscopic surgery (SILS) is a safe and effective alternative to multiport laparoscopic surgery (MPLS) for ovarian tissue cryopreservation.
- SILS may offer potential benefits in preserving larger volumes of ovarian tissue.
- Further prospective studies are warranted to confirm these findings and explore additional advantages.