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Isolation and characterization of an amphiphilic form of human intestinal aminopeptidase N

C Caporale1, R Troncone

  • 1Clinica Pediatrica, Universita' di Napoli, Italia.

An amphiphilic detergent-solubilized human adult intestinal microvillous aminopeptidase N (EC 3.4.11.2) was purified by immunoadsorbent technique using meconial aminopeptidase N antibodies. Its molecular and kinetic properties were investigated to confirm the differences previously observed from the meconial enzyme.

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