Jove
Visualize
Contact Us

Related Experiment Videos

Psychoactive drug interactions.

C T Gaultieri, S F Powell

    The Journal of Clinical Psychiatry
    |September 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Drug interactions can alter medication effectiveness or toxicity. Understanding these interactions is crucial for psychiatrists managing patients on stimulants, antidepressants, and other psychotropic medications.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Phase II study of elraglusib (9-ING-41), a GSK-3β inhibitor, in combination with gemcitabine plus nab-paclitaxel in previously untreated metastatic pancreatic cancer.

    ESMO open·2025
    Same author

    Pemetrexed plus platinum with or without pembrolizumab in patients with previously untreated metastatic nonsquamous NSCLC: protocol-specified final analysis from KEYNOTE-189.

    Annals of oncology : official journal of the European Society for Medical Oncology·2021
    Same author

    Induction of diploid androgenetic and mitotic gynogenetic Nile tilapia (Oreochromis niloticus L.).

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
    Same author

    Tin-polyimide and indium-polyimide thin-film composites as soft x-ray bandpass filters.

    Applied optics·2010
    Same author

    Is there a need for postoperative surveillance after day case groin surgery in children?

    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2002
    Same journal

    Major Depressive Disorder and PTSD Treatment Outcome in Interpersonal Psychotherapy and Prolonged Exposure.

    The Journal of clinical psychiatry·2026
    Same journal

    Psychiatrists and Medical Aid in Dying: Entering Uncharted Waters.

    The Journal of clinical psychiatry·2026
    Same journal

    Mind and Metabolism in Crisis: US Mortality Involving Obesity and Psychiatric Disorders-Trends, Disparities, and ARIMA Projections.

    The Journal of clinical psychiatry·2026
    Same journal

    Generative AI for the Clinical Psychopharmacologist: Is It Ready for Prime Time?

    The Journal of clinical psychiatry·2026
    Same journal

    Posttrauma Benzodiazepine Use and Subsequent PTSD: A Population-Wide Analysis Following Extreme Traumatic Exposure.

    The Journal of clinical psychiatry·2026
    Same journal

    The Challenges of PTSD Prevention: Placing Benzodiazepine Use in Context.

    The Journal of clinical psychiatry·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Pharmacology
    • Psychiatry
    • Clinical Pharmacy

    Background:

    • Drug interactions occur with simultaneous or sequential drug administration.
    • These interactions can modify a drug's therapeutic benefits or toxic effects.
    • Mechanisms include alterations in absorption, protein binding, metabolism, excretion, or receptor activity.

    Purpose of the Study:

    • To describe drug interactions relevant to psychiatric practice.
    • To provide a comprehensive overview of interactions involving common psychotropic medications.

    Main Methods:

    • Review of existing literature on drug interactions.
    • Categorization of interactions based on drug classes.

    Main Results:

    Related Experiment Videos

  • Drug interactions can significantly impact treatment outcomes in psychiatry.
  • Specific examples of interactions involving stimulants, neuroleptics, tricyclic antidepressants, monoamine oxidase inhibitors, lithium, anticonvulsants, and sedatives/hypnotics are discussed.

    • Conclusions:

    • Psychiatrists must be aware of potential drug interactions to optimize patient care.
    • Careful medication management is essential to prevent adverse events and enhance therapeutic efficacy.