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Related Experiment Videos

Microbiological look at urodynamic studies.

S R Payne1, A G Timoney, S T McKenning

  • 1Department of Urology, St Mary's Hospital, Portsmouth.

Lancet (London, England)
|November 12, 1988
PubMed
Summary

Urinary tract infections (UTIs) are common in women with detrusor instability and stress incontinence. Urodynamic investigations may lead to new bacterial infections, especially in men, suggesting antibiotic prophylaxis.

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Area of Science:

  • Urology
  • Infectious Diseases
  • Microbiology

Background:

  • Urinary tract infections (UTIs) are frequently associated with lower urinary tract symptoms.
  • Urodynamic investigations are standard procedures for evaluating bladder dysfunction.

Purpose of the Study:

  • To investigate the prevalence of bacteriuria before and after urodynamic investigations.
  • To assess the relationship between urodynamic findings and urinary tract infections.

Main Methods:

  • Urine samples were collected from 88 patients (66 female, 22 male) before and after urodynamic studies.
  • Cultures were performed for aerobic, fastidious, and anaerobic bacteria.
  • Bacteriuria status was correlated with clinical diagnoses such as detrusor instability, stress incontinence, and bladder outflow obstruction.

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Main Results:

  • Pre-investigation bacteriuria was found in 37/42 women with detrusor instability, 14/17 with stress incontinence, and 6/13 men with bladder outflow obstruction.
  • Post-investigation bacteriuria increased, with 36% of men and 15% of women acquiring aerobic bacterial infections.
  • A higher incidence of new bacterial acquisition was observed in men following urodynamic studies.

Conclusions:

  • Underlying urinary tract infections may cause irritative urinary symptoms attributed to urodynamic changes.
  • Urodynamic investigations carry a risk of inducing bacteriuria, particularly in male patients.
  • Consideration of antibiotic prophylaxis for men undergoing urodynamic studies is recommended.