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The causes of acute pancreatitis include:

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Updated: Feb 20, 2026

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Published on: April 28, 2020

Ascending Cholangitis due to Heavy Lifting.

M J Bakkum¹, R J L F Loffeld¹

¹Department of Internal Medicine, Zaans Medisch Centrum, Zaandam, the Netherlands.

Case Reports in Gastroenterology

|October 17, 2017

Summary

Gallstone disease commonly causes cholangitis. This case report details recurring cholangitis in a patient with a clear bile duct, suggesting duodenal reflux from heavy lifting as a potential cause after prior papillotomy.

Keywords:

Cholangitis Complicated gallstone disease Gallstones Heavy lifting

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Last Updated: Feb 20, 2026

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Published on: April 28, 2020

Area of Science:

Gastroenterology and Hepatology
Biliary System Pathophysiology

Background:

Gallstone disease is a primary risk factor for cholangitis.
Cholangitis typically requires the presence of gallstones in an anatomically normal bile duct.
Endoscopic retrograde cholangiography with papillotomy and stone extraction is a standard treatment for common bile duct stones.

Observation:

A 73-year-old male presented with recurrent cholangitis.
The patient had a history of prior papillotomy.
The bile duct system was found to be clear of stones.

Findings:

Recurrent cholangitis occurred despite the absence of gallstones.
The patient's bile duct system was anatomically normal.
A proposed etiology involves duodenal reflux into the common bile duct.

Implications:

This case highlights potential non-stone-related causes of cholangitis.
Duodenal reflux, possibly triggered by physical exertion like heavy lifting, may lead to recurrent cholangitis.
Further investigation into reflux-induced cholangitis is warranted.