Related Experiment Videos
Unchanged expression of Epstein-Barr virus-determined nuclear antigen-1 in productive virus cycle
Z Nováková1, V Krchnák, J Roubal
1Department of Experimental Virology, Institute of Sera and Vaccines, Prague, Czechoslovakia.
Acta Virologica
|July 1, 1988
Abstract:
The level of the Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA-1) encoded by the Bam HI-K fragment of EBV DNA remained unchanged in P3HR-1 cells after induction of the productive cycle of virus replication by sodium-n-butyrate and 12-o-tetradecanoylphorbol-13-acetate (TPA). This was shown by the same capacity of cell-free extracts from untreated and treated P3HR-1 cells to absorb anti-EBNA-1 antibody from a known human serum.