Related Experiment Videos
More Alcohol, More Liver Injury: Not Always True
Irina Kirpich1, Craig McClain2
1Department of Medicine, University of Louisville School of Medicine, 505S Hancock Street, CTR511, Louisville, KY 40202-1617, USA.
Alcohol and Alcoholism (Oxford, Oxfordshire)
|October 17, 2017
Abstract:
An animal model of alcoholic liver disease (ALD) that recapitulates human disease is an unmet need. An alcohol-preferring strain and WT mice were fed alcohol by different techniques and with different diet compositions. Interestingly, the greatest alcohol consumers did not develop the worst ALD. This editorial highlights how diet and the gut microbiome/metabolome may influence the development/severity of ALD.