Related Experiment Video
Updated: Aug 28, 2026
Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
DynaPho: a web platform for inferring the dynamics of time-series phosphoproteomics
Chia-Lang Hsu1, Jian-Kai Wang2, Pei-Chun Lu3
1Department of Life Science.
Summary:
Large-scale phosphoproteomics studies have improved our understanding of dynamic cellular signaling, but the downstream analysis of phosphoproteomics data is still a bottleneck. We develop DynaPho, a useful web-based tool providing comprehensive and in-depth analyses of time-course phosphoproteomics data, making analysis intuitive and accessible to non-bioinformatics experts. The tool currently implements five analytic modules, which reveal the transition of biological pathways, kinase activity, dynamics of interaction networks and the predicted kinase-substrate associations. These features can assist users in translating their larger-scale time-course phosphoproteomics data into valuable biological discoveries.
Availability And Implementation:
DynaPho is freely available at http://dynapho.jhlab.tw/ .
Contact:
hsuancheng@ym.edu.tw or yukijuan@ntu.edu.tw .
Supplementary Information:
Supplementary data are available at Bioinformatics online.
