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Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis
E Sahin1, D Dizdar2, M E Dinc3
1Department of Otolaryngology, Head and Neck Surgery,Bayındır Hospital Icerenkoy,Istanbul,Turkey.
Background:
Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis.
Methods:
The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients).
Results:
The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p 0.0175).
Conclusion:
Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.
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