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[Results of Partial Atrial Resection in Advanced Lung Cancer]
Yoshio Tsunezuka1, Nobuhiro Tanaka, Hideki Fujimori
1Department of General Thoracic Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Abstract:
The present study analyzed double centers experiences with extended combined resection of the left atrium in patients with lung cancer. From January 1972 to May 2017, 32 patients underwent lung resection with partial resection of the left atrium for lung cancer. Of them,( median age 62 years, range 40 to 79 years), 25 were men (78%) and 7 were women. Twenty-three pneumonectomies (72%)were performed, of which 19 (59%) were right sided. Dissection of the interatrial groove was completed in 4 patients( 36.3%). Extracorporeal circulation system was used in 4 patients( 12%). Pathological analysis of resected lymph nodes identified 6 patients (19%) with N0, 13 patients with N1 (40%) and 13 patients with N2( 40%). There were 17 squamous cell carcinomas( 53%), 8 adenocarcinomas( 25%), 3 pleomorphic carcinomas, 1 large cell carcinoma, 1 mucoepidermoid carcinoma, adenosquamous cell carcinoma and 1 combined small cell carcinoma and adenocarcinoma. Two patients underwent induction chemotherapy and 26 patients( 81.2%) underwent adjuvant treatment. With a median follow-up of 21.8 months (0~120), the 3 and 5-year survival rate after the surgical resection was 13.7% and 23.8 %. Since January 2000, 11 patients were operated, 3 and 5-year survival rate was 50.0 and 36.3%. Histological N0-1 was associated with better median overall survival(OS) compared with N2, with a corresponding 5-year OS rate of 18.9 and 7.7%, respectively.