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Mini Review - Phenolics for skin photo-aging
1Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
Abstract:
Photo-aging is one of the foremost problems caused by generation of reactive oxygen species when skin is exposed on UV irradiation. In view of that, generation of reactive oxygen species intermingle with proteins, DNA, saccharides and fatty acids triggering oxidative mutilation and effects are in the appearance of distressed cell metabolism, morphological and ultra-structural changes, mistreat on the routes and revisions in the demarcation, propagation and skin apoptosis living cells which leads to photo-aging. Plant phenolics are universally found in both edible and inedible plants and have extended substantial interest as photo-protective for human skin due to their antioxidant activities. The objective of this review is to highlight the use of plant phenolics for their antioxidant activities against photo-aging.
Insights
UV irradiation causes skin photo-aging by generating reactive oxygen species. Plant phenolics offer antioxidant protection against this damage, making them valuable for skin health.
Area of Science:
- Dermatology
- Biochemistry
- Plant Science
Background:
- Photo-aging, a significant skin concern, results from reactive oxygen species (ROS) generated by UV exposure.
- ROS interact with cellular components, leading to oxidative damage, altered cell metabolism, and structural changes.
- This cellular damage contributes to the visible signs of photo-aging and affects skin cell functions like proliferation and apoptosis.
Purpose of the Study:
- To review the role of plant phenolics in combating photo-aging.
- To highlight the antioxidant properties of plant phenolics for skin protection.
Main Methods:
- Literature review focusing on studies investigating plant phenolics and their effects on UV-induced skin damage.
- Analysis of research on the antioxidant mechanisms of plant phenolics.
Main Results:
- Plant phenolics possess significant antioxidant activities.
- These compounds can mitigate ROS-induced oxidative stress in skin cells.
- Evidence suggests plant phenolics can protect against the detrimental effects of UV irradiation on skin.
Conclusions:
- Plant phenolics are promising natural agents for photo-protection.
- Their antioxidant capacity makes them effective in preventing and potentially reversing photo-aging.
- Further research into specific plant phenolics could lead to novel skincare applications.