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Mini Review - Phenolics for skin photo-aging
1Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
Pakistan Journal of Pharmaceutical Sciences
|October 18, 2017
Summary
UV irradiation causes skin photo-aging by generating reactive oxygen species. Plant phenolics offer antioxidant protection against this damage, making them valuable for skin health.
Area of Science:
- Dermatology
- Biochemistry
- Plant Science
Background:
- Photo-aging, a significant skin concern, results from reactive oxygen species (ROS) generated by UV exposure.
- ROS interact with cellular components, leading to oxidative damage, altered cell metabolism, and structural changes.
- This cellular damage contributes to the visible signs of photo-aging and affects skin cell functions like proliferation and apoptosis.
Purpose of the Study:
- To review the role of plant phenolics in combating photo-aging.
- To highlight the antioxidant properties of plant phenolics for skin protection.
Main Methods:
- Literature review focusing on studies investigating plant phenolics and their effects on UV-induced skin damage.
- Analysis of research on the antioxidant mechanisms of plant phenolics.
Main Results:
- Plant phenolics possess significant antioxidant activities.
- These compounds can mitigate ROS-induced oxidative stress in skin cells.
- Evidence suggests plant phenolics can protect against the detrimental effects of UV irradiation on skin.
Conclusions:
- Plant phenolics are promising natural agents for photo-protection.
- Their antioxidant capacity makes them effective in preventing and potentially reversing photo-aging.
- Further research into specific plant phenolics could lead to novel skincare applications.