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Published on: August 9, 2024
Targeted identification of adverse events in coronary artery disease patients based on patient-reported outcomes
Jari Heiskanen1,2, Anna-Maija Tolppanen2, Janne Martikainen3
1Heart Center, Kuopio University Hospital, Kuopio, Finland.
Insights
Focusing adverse event searches on patients with poor patient-reported outcomes can improve detection rates. This approach aids in identifying more adverse events for efficient learning and enhanced patient safety.
Area of Science:
- Cardiovascular Surgery
- Patient Safety
- Health Outcomes Research
Background:
- Adverse event detection is crucial for learning and improving patient care.
- Patient-reported outcomes (PROs) offer valuable insights into patient experiences post-intervention.
Purpose of the Study:
- To investigate if focusing adverse event searches on patients with poor PROs enhances adverse event detection.
Main Methods:
- Patients undergoing coronary artery revascularization were categorized based on changes in health-related quality of life (15D score).
- Groups included those with clinically significant improvement (≥0.015) and deterioration (≥-0.015).
- Adverse event rates were compared between these groups.
Main Results:
- Patients with deteriorated PROs experienced significantly higher rates of major complications (27% vs 9%) and post-intervention infections (16% vs 5%).
- A trend towards more cardiovascular and minor complications was observed in the deteriorated PRO group.
Conclusions:
- Patient-reported outcomes can effectively target adverse event searches.
- This targeted approach facilitates the identification of a greater number of adverse events, enabling more efficient learning and improved patient safety.
Aim:
Can focusing the adverse events search to patients with poor patient-reported outcome help in targeting adverse event detection?
Patients & Methods:
Coronary artery revascularization patients of the Kuopio University Hospital from June 2012 to August 2014 categorized into those with clinically significant improvement (15D score change ≥0.015, n = 81) or deterioration (change ≥-0.015, n = 64) in post-intervention health-related quality of life.
Results:
Major complications (27 vs 9%, p = 0.004) or post-intervention infections (16 vs 5%, p = 0.031) were more common among those with deteriorated score. They also tended to have more cardiovascular (19 vs 9%, p = 0.071) and minor complications (16 vs 7%, p = 0.118).
Conclusion:
Patient-reported outcomes may potentially help in targeting the adverse events search so that a larger number of adverse events can be identified for efficient learning from them.
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