Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of porous aluminate microbeads from emulsion droplets: interphase alcohol extraction-driven assembly of sub-10 nm nanoparticles.

RSC advances·2026
Same author

CD44-Binding Peptide-Functionalized Antibiofouling Polymer Surface for High-Performance Separation of Human Mesenchymal Stromal Cells.

Chembiochem : a European journal of chemical biology·2026
Same author

Geometry-dependent regulation of myogenic and osteogenic differentiation on microgeometry polystyrene substrates.

Biomedical microdevices·2026
Same author

Branched sulfoisobutylbetaine acrylamide polymers with hydrolytically stable amide linkages for long-term durable anti-biofouling surfaces.

Journal of materials chemistry. B·2026
Same author

Durable and biofunctional polydimethylsiloxane surfaces engineered with photocrosslinkable terpolymers for aligned and functional myotube formation.

Biomaterials and biosystems·2026
Same author

Nanoparticle Percolation Improves the Mechanical Properties of Polymer Nanocomposite Films.

ACS macro letters·2025

Related Experiment Video

Updated: Feb 20, 2026

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.7K

A novel approach for UV-patterning with binary polymer brushes.

Lifu Li1, Tadashi Nakaji-Hirabayashi2, Hiromi Kitano3

  • 1Graduate School of Innovative Life Sciences, University of Toyama, Toyama 930-8555, Japan.

Colloids and Surfaces. B, Biointerfaces
|October 18, 2017
PubMed
Summary
This summary is machine-generated.

Researchers developed a simple method to pattern surfaces with polymer brushes using UV light. This technique creates distinct anti-fouling and non-polar domains, useful for controlling protein and cell adhesion on various materials.

Keywords:
Atom transfer radical polymerization (ATRP)Cell adhesionPatterning with binary polymer brushesReversible addition-fragmentation chain transfer (RAFT) polymerizationUV irradiation

More Related Videos

Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures
07:23

Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures

Published on: November 14, 2025

432
Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
13:57

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes

Published on: December 24, 2014

14.4K

Related Experiment Videos

Last Updated: Feb 20, 2026

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.7K
Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures
07:23

Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures

Published on: November 14, 2025

432
Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
13:57

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes

Published on: December 24, 2014

14.4K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Surface Chemistry

Background:

  • Developing patterned surfaces with controlled polymer brushes is crucial for advanced material applications.
  • Existing methods for surface patterning can be complex and lack versatility.

Purpose of the Study:

  • To create a facile and effective method for patterning solid surfaces with distinct polymer brush domains.
  • To demonstrate the sequential surface-initiated polymerization of different polymer types on demand.

Main Methods:

  • Constructed a mixed self-assembled monolayer (SAM) of initiators for atom transfer radical polymerization (ATRP) and reversible addition-fragmentation chain transfer (RAFT) polymerization.
  • Utilized UV light irradiation through a photomask to selectively activate polymerization sites by cleaving initiator bonds.
  • Performed sequential surface-initiated ATRP of 2-ethylhexyl methacrylate (EHMA) and SI-RAFT polymerization of carboxymethyl betaine (CMB).

Main Results:

  • Achieved precise patterning of poly(EHMA) (PEHMA) and poly(CMB) (PCMB) brush domains on silicon wafer or glass substrates.
  • Demonstrated UV-driven reduction of initiator density in irradiated regions via X-ray photoelectron spectroscopy.
  • Confirmed the successful sequential polymerization leading to binary polymer brush patterns.

Conclusions:

  • The developed technique offers a simple and versatile approach for creating patterned surfaces with binary polymer brushes.
  • The patterned PCMB and PEHMA brushes exhibit distinct properties, including anti-fouling and non-polar characteristics.
  • This method is highly applicable for regulating biofouling and anti-biofouling domains on solid surfaces, with potential for protein and cell patterning.