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New adhesive system based in metals cross-linking methacrylate
Alexandra Rubin Cocco1, Wellington Luiz de Oliveira da Rosa1, Sônia Luque Peralta1
1Post-Graduate Program in Dentistry, Department of Restorative Dentistry, Dental School, Federal University of Pelotas, Pelotas, RS, Brazil.
Journal of the Mechanical Behavior of Biomedical Materials
|October 18, 2017
Summary
Silver and tin methacrylates show anti-biofilm potential in dental adhesives. At 1%, these additives combat Mutans streptococci without negatively impacting mechanical properties or cell viability.
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
- Antimicrobial Research
Background:
- Dental caries and periodontal diseases are often linked to bacterial biofilms.
- Developing effective antimicrobial strategies within dental adhesive systems is crucial for long-term restoration success.
- Incorporating antimicrobial agents into adhesive resins offers a promising approach to prevent biofilm formation.
Purpose of the Study:
- To evaluate the anti-biofilm potential of silver methacrylate (Ag) and di-n-butyldimethacrylatetin (Sn) incorporated into experimental adhesive systems.
- To assess the impact of these metal methacrylates on the physical, mechanical, and biological properties of the adhesive resin.
- To determine the optimal concentration for achieving anti-biofilm effects without compromising material integrity.
Main Methods:
- Ag and Sn methacrylates were added to an adhesive resin at 0.5%, 1%, and 2% concentrations.
- Evaluated properties included anti-biofilm potential, degree of conversion (DC), microtensile bond strength (μTBS), water sorption/solubility (WSR/SL), and cytotoxicity.
- Scanning Electron Microscopy (SEM) was used to analyze bonded interfaces, and ion leaching was quantified.
Main Results:
- Ag and Sn methacrylates at 1% and 2% concentrations demonstrated anti-biofilm activity against Mutans streptococci.
- Ag at 2% concentration negatively affected DC and μTBS.
- Water sorption/solubility was significantly affected by Ag (1%, 2%) and Sn (2%), while cytotoxicity remained comparable to controls across all tested concentrations.
- Silver ion leaching was significantly higher than tin ion leaching.
Conclusions:
- Silver and tin methacrylates, particularly at 1% concentration, exhibit promising anti-biofilm effects in dental adhesive systems.
- The 1% concentration of Ag and Sn methacrylates provides an anti-biofilm effect without compromising key mechanical properties or cell viability.
- Further research is warranted to optimize metal methacrylate concentrations and investigate long-term clinical performance and safety profiles.
Keywords:
Antibacterial adhesive dentalAntibacterial monomersChemical propertiesDental materialsMechanical propertiesMore Related Videos
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