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Reduced expression of NR4A1 activates glycolytic pathway in acute promyelocytic leukemia cells

Flávia Adolfo Corrocher1, Luciana Bueno de Paiva1, Adriana Silva Santos Duarte1

  • 1a Instituto Nacional de Ciência e Tecnologia do Sangue , Hematology and Blood Transfusion Center-University of Campinas/Hemocentro-Unicamp , Campinas , Brazil.

Leukemia & Lymphoma
|October 19, 2017
PubMed
Abstract

No abstract available in PubMed .

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Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

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