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Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Nuclear Transmutation03:20

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Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
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Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Related Experiment Video

Updated: Feb 20, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
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Theranostics in nuclear medicine practice.

Anna Yordanova1, Elisabeth Eppard2, Stefan Kürpig2

  • 1Department of Nuclear Medicine (Clinical Nuclear Medicine).

Oncotargets and Therapy
|October 19, 2017
PubMed
Summary
This summary is machine-generated.

Personalized medicine, particularly nuclear theranostics, offers targeted diagnostics and therapies to improve patient outcomes and reduce costs. This approach enhances treatment selection and effectiveness in oncology.

Keywords:
PET/CTdiagnosticsnuclear medicinepersonalized medicinetheranosticstherapy

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Area of Science:

  • Nuclear medicine
  • Oncology
  • Personalized medicine

Background:

  • Growing need for personalized medicine to avoid ineffective treatments.
  • Theranostics in nuclear medicine enables specific molecular targeting for diagnosis and therapy.
  • Advancements in radiopharmaceuticals and imaging drive the increasing use of theranostic agents.

Purpose of the Study:

  • To highlight key milestones in nuclear diagnostics and therapies within theranostics.
  • To summarize background knowledge and current applications of theranostic approaches.
  • To identify the advantages of targeted therapies and imaging in nuclear medicine.

Main Methods:

  • Review of established nuclear therapies, starting with radioiodine therapy for thyroid cancer.
  • Exploration of various targeted therapy approaches for advanced cancers.
  • Analysis of diagnostic imaging techniques for predicting treatment response.

Main Results:

  • Radioiodine therapy for thyroid cancer serves as a foundational example of theranostics.
  • Targeted therapies demonstrate significant potential in treating advanced cancers.
  • Diagnostic imaging is crucial for predicting patient benefit from specific treatments.

Conclusions:

  • Theranostics is a vital tool in personalized medicine, improving treatment efficacy.
  • Nuclear medicine practices benefit significantly from targeted therapies and advanced imaging.
  • Continued development in radiopharmaceuticals and diagnostics will further advance theranostic applications.