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Updated: Feb 20, 2026

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
Published on: September 18, 2021
Cognitive Stimulation as a Therapeutic Modality for Dementia: A Meta-Analysis
Kayoung Kim1, Ji Won Han2, Yoonseop So3
1Department of Geriatric Psychiatry, National Center for Mental Health, Seoul, Republic of KoreaDepartment of Geriatric Psychiatry, National Center for Mental Health, Seoul, Republic of Korea.
Cognitive stimulation (CS) offers moderate benefits for people with dementia, improving cognition and quality of life. This meta-analysis confirms CS as an effective intervention for dementia care.
Area of Science:
- Neuroscience
- Gerontology
- Psychiatry
Background:
- Cognitive stimulation (CS) is a widely adopted non-pharmacological approach for dementia management.
- The precise efficacy of CS in improving cognitive function and quality of life for individuals with dementia remains a subject of ongoing research and debate.
Purpose of the Study:
- To conduct a meta-analysis of randomized controlled trials (RCTs) to evaluate the effectiveness of cognitive stimulation in people diagnosed with dementia.
- To synthesize evidence regarding the impact of CS on cognitive performance and quality of life in dementia patients.
Main Methods:
- A systematic literature search was conducted across major databases including PubMed, MEDLINE, Embase, psychINFO, and Cochrane Reviews Library.
- 30 RCTs were initially identified, with 14 studies meeting the inclusion criteria for the meta-analysis, involving 731 participants with dementia.
- Participants were allocated to either a cognitive stimulation group (412) or a usual care control group (319).
Main Results:
- Cognitive stimulation demonstrated a moderate positive effect on cognitive function, as measured by the Alzheimer's Disease Assessment Scale-Cognition (ADAS-Cog) and Mini-Mental State Examination (MMSE).
- Significant improvements were observed in the CS group compared to the control group for both ADAS-Cog (mean difference = 2.21) and MMSE (mean difference = 1.41).
- CS also led to a statistically significant improvement in the quality of life for individuals with dementia.
Conclusions:
- Cognitive stimulation is an effective intervention for enhancing both cognitive abilities and quality of life in people with dementia.
- While effective, the observed effects of CS on cognition and quality of life in dementia patients are generally considered small to moderate.
- The findings support the integration of CS as a valuable component of non-pharmacological dementia care strategies.
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