Evaluation of the hemodynamics and right ventricular function in pulmonary hypertension by echocardiography compared...

The present study aimed to evaluate hemodynamics and right ventricular function in patients with pulmonary hypertension (PH) using transthoracic echocardiography and to compare these results with measurements obtained using right-sided heart catheterization (RHC). A total of 75 patients with PH were examined using echocardiography and RHC. Patients were divided into the following two groups according to their difference between SPAP_echo and SPAP_RHC measurement: The overestimated group and underestimated group. The overestimated group included the subgroups group_over-A (difference <20 mmHg) and group_over-B (difference ≥20 mmHg), and the underestimated group included group_under-A (absolute value of the difference <20 mmHg) and group_under-B (absolute value of the difference ≥20 mmHg). SPAP_echo measurements were revealed to be significantly positively correlated with SPAP_RHC measurements (r=0.794; P<0.01). Among all echocardiographic measurements, only tricuspid annular plane systolic excursion (TAPSE) was significantly different between groups; it was increased in group_over-A and group_under-A compared with group_over-B (P<0.01). Although SPAP measurements obtained using echocardiography were significantly positively correlated with those obtained using RHC, a high proportion of overestimation or underestimation of SPAP by echocardiography remained.